Cardiovascular and neuropsychiatric risks of varenicline – Authors' reply

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Cardiovascular and neuropsychiatric risks of varenicline: a retrospective cohort study

BACKGROUND Varenicline is an effective pharmacotherapy to aid smoking cessation. However, its use is limited by continuing concerns about possible associated risks of serious adverse cardiovascular and neuropsychiatric events. The aim of this study was to investigate whether use of varenicline is associated with such events. METHODS In this retrospective cohort study, we used data from patien...

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Cardiovascular and neuropsychiatric risks of varenicline and bupropion in smokers with chronic obstructive pulmonary disease.

BACKGROUND Varenicline and bupropion are effective smoking cessation treatments, but there are concerns about their safety in smokers with COPD. OBJECTIVE To investigate whether varenicline and bupropion are associated with serious adverse cardiovascular and neuropsychiatric events in smokers with COPD. METHODS In a retrospective cohort study, we used data from 14 350 patients with COPD inc...

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ژورنال

عنوان ژورنال: The Lancet Respiratory Medicine

سال: 2016

ISSN: 2213-2600

DOI: 10.1016/s2213-2600(16)00056-4